Detection on Electroplating Effluent-Induced Cytopathological Alterations and DNA Damage in the Blood Samples of Cirrhinus mrigala (Hamilton, 1822)

In the present study, fresh waterfish Cirrhinus mrigala has been used as a model organism to understand mechanistic link between electroplating industrial effluent (EIE) and oxidative stress in aquatic ecosystems. To this end, fishes were exposed effluent, tank water for 10, 20 30 days under controlled laboratory conditions. Various hematological parameters (Total RBC WBC, Hemoglobin, MCV, MCH, PCV), biochemical metabolites (Glucose, protein, Cholesterol) markers of genotoxicity (comet assay micronuclear assay) assessed. Fishes showed marked increase (p <0.001) with concomitant decrease total WBC. There is significant decline indices blood cells such Hb, MCH PCV. Results from comet significantly < 0.05) increased frequency erythrocytes evident observed tail length EIE days. Overall, results clearly demonstrated concentration dependent response on freshwater fish haematological, genotoxic markers. The obtained herein suggests potential xenobiotics contributing towards ecotoxic effect fishes.